All content material in order that it’s beneficial to a substantially wider population. The Norgestimate Protocol European principles of management of headache issues in key care, laid out in 11 sections, would be the core from the content material. Every single of these is more-or-less stand-alone, in an effort to act as practicalThe Journal of Headache and Discomfort 2017, 18(Suppl 1):Page ten ofmanagement aids too as educational resources. There is a set of further sensible management aids. An abbreviated version from the International Classification of Headache Problems, 3rd edition (ICHD3), gives diagnostic criteria for the handful of headache disorders relevant to main care. A headache diary additional assists diagnosis as well as a headache calendar assists follow-up. A measure of headache influence (the HALT-90 index) may be employed in pre-treatment assessment of illness severity, and an outcome measure (the HURT questionnaire) is often a guide to follow-up and want for treatment-review. 5 patient information and facts leaflets are integrated, which could be supplied to individuals to improve their understanding of their headache problems and their management. LTB and EHF give these aids freely offered for use with no restriction. We hope for advantages for both physicians and sufferers. S33 Combined hormonal contraception and migraine, WHO and EHF ESCRH criteria and balancing dangers and benefit Simona Sacco ([email protected]) Neurology section, Division of Applied Clinical Science and Biotechnology, University of L’Aquila, L’Aquila, Italy The Journal of Headache and Pain 2017, 18(Suppl 1):S33 Various data indicate that migraine, specifically migraine with aura, is connected with an improved danger of ischemic stroke as well as other vascular events. Of concern is no matter if the danger of ischemic stroke in migraineurs is magnified by the use of hormonal contraceptives (HCs). As migraine prevalence is higher in girls of reproductive age, it is common to face the problem of migraine and HC use in clinical practice. To enhance decision-making around the use of HCs in girls with migraine, a selected group of representatives from the European Headache Federation (EHF) along with the European Society of Contraception and Reproductive Well being (ESC) created a Consensus Statement on this topic. The document pointed out that proof addressing the threat of ischemic stroke related using the use of HCs is usually poor. All information and facts relies on observational information, which may well carry the threat of prospective bias. Offered studies had (Ethoxymethyl)benzene Purity & Documentation diverse settings and used diverse groups for comparing risks, limiting reputable comparison of research as a pooled evaluation of information. Most of the readily available studies have been published quite a few years ago and utilised compounds which are distinctive from these out there today. Also, in most research not sufficient info is readily available concerning the kind of HC viewed as and in most instances benefits usually are not supplied according to migraine form. In spite of these limitations, available information pointed toward an elevated threat of ischemic stroke related using the use of HCs in ladies with migraine. Literature indicated that, whereas combined HCs carry a particular danger of arterial ischemic events this will not occur for progestogens-only HCs which are regarded protected when it comes to cardiovascular risk even within the presence of linked risk variables. Thinking about those information, and unless studies will prove safety of the use of combined HCs in women with migraine, the suggestions in the Consensus Group gave priority to security and suggested various limit.