Sions, manual or CD) since it ended Is there something you’d do differently Is there anything you’d add in Searching back, do you really feel which you took part within the intervention at the appropriate time We subsequently sent all TA-02 participants a transcript of their original response in conjunction with a freepost envelope, asking them no matter if it was representative of their true views and to create amendments if they wished. This process of top quality handle and validation allowsMETHODS Setting and intervention The Start off study was a pragmatic multicentre RCT evaluating the effect on dementia carers’ affectiveSommerlad A, Manela M, Cooper C, et al. BMJ Open 2014;4:e005273. doi:10.1136bmjopen-2014-Open Access participants to ensure that the transcript is what they intended to say. We also sent questionnaires to the participants who had previously withdrawn from the study asking the following inquiries: What did you assume of your assistance sessions and manual No matter if you did or didn’t attend the support sessions, was there anything we ought to change to create it extra beneficial to you We evaluated questionnaire responses alongside sociodemographic and clinical data, including time since diagnosis of dementia, carers’ anxiety and depression– measured by the Hospital Anxiety and Depression Scale (HADS),15 a self-rated scale which has been validated for use in a selection of settings–and the severity of patients’ dementia–measured by the clinical dementia rating (CDR),16 which grades the degree of impairment connected to dementia. These quantitative data were collected at baseline and at 24 months inside the original study. Analysis We transcribed the returned questionnaires verbatim and applied a thematic framework approach17 for evaluation. Two researchers (AS and MM) independently read the transcripts and identified a framework of initial themes which referred for the PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21330824 primary study objectives. The researchers then made use of the qualitative software package NVivo (QSR International Pty Ltd, V.9, 2010) to code the transcripts in accordance with these themes and jointly developed a thematic map with a hierarchy of themes and categories. We have anonymised all quotations, offering non-specific demographic details, and usually do not think that any carer may be identified. variations in other demographic or clinical traits weren’t statistically significant. We received only 1 response from a participant who withdrew; this person completed the Start off programme but withdrew in the study before the 24-month follow-up interview. None of the participants who had initially returned a completed questionnaire produced notable adjustments to their responses when invited to complete so. Participants’ comments are detailed under and captured inside 4 broad themes: significant aspects on the therapy, participants’ engagement with all the therapy, unhelpful aspects of therapy and possible improvements and appropriate time for delivery of the intervention. Selected quotes are made use of here to illustrate important viewpoints. We’ve annotated quotes to describe the participants’ function (`w’ wife, `h’ husband’, `d’ daughter, `s’ son, `n’ niece) and numbered participants within the order in which the quotes are employed, the severity of dementia at baseline plus the carer’s total HADS score at the baseline interview and 24-month follow-up (eg, `HADS 12 7’=HADS score of 12 at baseline and 7 at the 24-month interview). The HADS score at 12 months has been offered for two participants who did not total HADS at 24 months. Imp.