HMS LINCS ID: 10037-101

Name: AC220

Alternative Names:

LINCS ID: LSM-1037

PubChem CID: 24889392

ChEBI ID:

ChEMBL ID:

Molecular Mass: 560.22

InChi: InChI=1S/C29H32N6O4S/c1-29(2,3)25-17-26(33-39-25)32-27(36)30-20-6-4-19(5-7-20)22-18-35-23-9-8-21(16-24(23)40-28(35)31-22)38-15-12-34-10-13-37-14-11-34/h4-9,16-18H,10-15H2,1-3H3,(H2,30,32,33,36)

InChi Key: CVWXJKQAOSCOAB-UHFFFAOYSA-N

SMILES: CC(C)(C)C1=CC(=NO1)NC(=O)NC2=CC=C(C=C2)C3=CN4C5=C(C=C(C=C5)OCCN6CCOCC6)SC4=N3

Relevant Citations:

Date Publicly Available:

Most Recent Update: 2016-04-04

HMS LINCS ID: 10036-101

Name: SB 239063

Alternative Names:

LINCS ID: LSM-1036

PubChem CID: 5166

ChEBI ID:

ChEMBL ID:

Molecular Mass: 368.16

InChi: InChI=1S/C20H21FN4O2/c1-27-20-22-11-10-17(24-20)19-18(13-2-4-14(21)5-3-13)23-12-25(19)15-6-8-16(26)9-7-15/h2-5,10-12,15-16,26H,6-9H2,1H3

InChi Key: ZQUSFAUAYSEREK-UHFFFAOYSA-N

SMILES: COC1=NC=CC(=N1)C2=C(N=CN2C3CCC(CC3)O)C4=CC=C(C=C4)F

Relevant Citations:

Date Publicly Available:

Most Recent Update: 2016-04-04

HMS LINCS ID: 10035-101

Name: Sigma A6730

Alternative Names: KIN001-102; AKT inhibitor VIII; Akt1/2 kinase inhibitor

LINCS ID: LSM-1035

PubChem CID: 10196499

ChEBI ID:

ChEMBL ID: 258844

Molecular Mass: 551.24

InChi: InChI=1S/C34H29N7O/c42-34-39-26-8-4-5-9-31(26)41(34)25-14-16-40(17-15-25)20-22-10-12-24(13-11-22)33-32(23-6-2-1-3-7-23)37-29-18-27-28(36-21-35-27)19-30(29)38-33/h1-13,18-19,21,25H,14-17,20H2,(H,35,36)(H,39,42)

InChi Key: BIWGYFZAEWGBAL-UHFFFAOYSA-N

SMILES: C1CN(CCC1N2C3=CC=CC=C3NC2=O)CC4=CC=C(C=C4)C5=NC6=CC7=C(C=C6N=C5C8=CC=CC=C8)N=CN7

Relevant Citations:

Date Publicly Available:

Most Recent Update: 2016-04-04

HMS LINCS ID: 10078-101

Name: THZ-2-98-01

Alternative Names:

LINCS ID: LSM-5601

PubChem CID:

ChEBI ID:

ChEMBL ID:

Date Publicly Available:

Most Recent Update: 2016-04-04

HMS LINCS ID: 10033-101

Name: KIN001-055

Alternative Names:

LINCS ID: LSM-1033

PubChem CID: 3796

ChEBI ID:

ChEMBL ID:

Molecular Mass: 452.93

InChi: InChI=1S/C16H13Br2N3O3/c1-23-13-5-9-12(6-14(13)24-2)19-7-20-16(9)21-8-3-10(17)15(22)11(18)4-8/h3-7,22H,1-2H3,(H,19,20,21)

InChi Key: YVCXQRVVNQMZEI-UHFFFAOYSA-N

SMILES: COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C(=C3)Br)O)Br)OC

Relevant Citations:

Date Publicly Available:

Most Recent Update: 2016-04-04

HMS LINCS ID: 10032-101

Name: Saracatinib

Alternative Names: AZD0530

LINCS ID: LSM-1032

PubChem CID: 10302451

ChEBI ID:

ChEMBL ID: 217092

Molecular Mass: 541.21

InChi: InChI=1S/C27H32ClN5O5/c1-32-6-8-33(9-7-32)10-13-35-19-14-21-24(23(15-19)38-18-4-11-34-12-5-18)27(30-16-29-21)31-25-20(28)2-3-22-26(25)37-17-36-22/h2-3,14-16,18H,4-13,17H2,1H3,(H,29,30,31)

InChi Key: OUKYUETWWIPKQR-UHFFFAOYSA-N

SMILES: CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6

Relevant Citations:

Date Publicly Available:

Most Recent Update: 2016-04-04

HMS LINCS ID: 10031-101

Name: KIN001-043

Alternative Names:

LINCS ID: LSM-1031

PubChem CID: 24906282

ChEBI ID:

ChEMBL ID:

Molecular Mass: 355.00

InChi: InChI=1S/C16H10BrN3O2/c17-8-5-6-9-12(7-8)19-16(21)13(9)15-14(20-22)10-3-1-2-4-11(10)18-15/h1-7,20,22H,(H,19,21)

InChi Key: WNWSUJQVZJJGLF-UHFFFAOYSA-N

SMILES: C1=CC2=C(C(=C3C4=C(C=C(C=C4)Br)NC3=O)N=C2C=C1)NO

Relevant Citations:

Date Publicly Available:

Most Recent Update: 2016-04-04

HMS LINCS ID: 10030-101

Name: KIN001-042

Alternative Names:

LINCS ID: LSM-1030

PubChem CID: 6539732

ChEBI ID:

ChEMBL ID:

Molecular Mass: 394.96

InChi: InChI=1S/C14H10IN3OS/c15-12-3-1-2-10(8-12)9-20-14-18-17-13(19-14)11-4-6-16-7-5-11/h1-8H,9H2

InChi Key: ZRHRPGSSSVYBRG-UHFFFAOYSA-N

SMILES: C1=CC(=CC(=C1)I)CSC2=NN=C(O2)C3=CC=NC=C3

Relevant Citations:

Date Publicly Available:

Most Recent Update: 2016-04-04

HMS LINCS ID: 10029-101

Name: GW-5074

Alternative Names:

LINCS ID: LSM-1029

PubChem CID: 5034

ChEBI ID:

ChEMBL ID:

Molecular Mass: 518.80

InChi: InChI=1S/C15H8Br2INO2/c16-11-4-7(5-12(17)14(11)20)3-10-9-6-8(18)1-2-13(9)19-15(10)21/h1-6,20H,(H,19,21)

InChi Key: LMXYVLFTZRPNRV-UHFFFAOYSA-N

SMILES: C1=CC2=C(C=C1I)C(=CC3=CC(=C(C(=C3)Br)O)Br)C(=O)N2

Relevant Citations:

Date Publicly Available:

Most Recent Update: 2016-04-04

HMS LINCS ID: 10028-102

Name: BMS345541

Alternative Names:

LINCS ID: LSM-1028

PubChem CID: 9813758

ChEBI ID:

ChEMBL ID:

Molecular Mass: 255.15

InChi: InChI=1S/C14H17N5/c1-9-3-4-11-12(7-9)19-10(2)8-17-14(19)13(18-11)16-6-5-15/h3-4,7-8H,5-6,15H2,1-2H3,(H,16,18)

InChi Key: PSPFQEBFYXJZEV-UHFFFAOYSA-N

SMILES: CC1=CC2=C(C=C1)N=C(C3=NC=C(N23)C)NCCN

Relevant Citations:

Date Publicly Available:

Most Recent Update: 2016-04-04