All posts by Proton-pump inhibitor

Stachybotrylactam

Stachybotrylactam
Stachybotrylactam is an unusual spirodihydrobenzofuranlactam mycotoxin isolated from a Stachybotrys sp. that has immunosuppressant and weak HIV protease activity. Members of this structural class show diverse activity including antiviral, endothel
Afatinib

Filipin

Filipin
Filipin complex comprises a family of pentaene macrocyclic lactones first isolated from Streptomyces filipinensis and reported by researchers at Upjohn in 1955. Filipin complex consists of four analogues, with filipin III comprising the bulk (&gt
Etomoxir

Filipin

Filipin
Filipin complex comprises a family of pentaene macrocyclic lactones first isolated from Streptomyces filipinensis and reported by researchers at Upjohn in 1955. Filipin complex consists of four analogues, with filipin III comprising the bulk (&gt
Etomoxir

Emodin

Emodin
Emodin is a tyrosine kinase inhibitor found in multiple plants with a variety of bioactivity including anti-inflammatory, antiviral, antibacterial and anticancer activity. As an anticancer agent it has drawn attention by showing promising therapeu
GBT 440

Emodin

Emodin
Emodin is a tyrosine kinase inhibitor found in multiple plants with a variety of bioactivity including anti-inflammatory, antiviral, antibacterial and anticancer activity. As an anticancer agent it has drawn attention by showing promising therapeu
GBT 440

Filipin II

Filipin II
Filipin II is a minor component of the filipin complex, a family of pentaene antifungal metabolites first isolated from Streptomyces filipinensis and reported by researchers at Upjohn in 1955. Structurally, filipin II lacks the hydroxy moiety on t
MK-5172

Filipin II

Filipin II
Filipin II is a minor component of the filipin complex, a family of pentaene antifungal metabolites first isolated from Streptomyces filipinensis and reported by researchers at Upjohn in 1955. Structurally, filipin II lacks the hydroxy moiety on t
MK-5172

Embelin

Embelin
Embelin is a benzoquinone derivative from the Japanese Ardisia herb. It is a cell-permeable, small-molecule inhibitor of apoptosis regulator proteins. It is a promising start to a new class of anticancer drugs that target apoptosis regulator prote
CHIR-99021

Embelin

Embelin
Embelin is a benzoquinone derivative from the Japanese Ardisia herb. It is a cell-permeable, small-molecule inhibitor of apoptosis regulator proteins. It is a promising start to a new class of anticancer drugs that target apoptosis regulator prote
CHIR-99021

Steffimycin B

Steffimycin B
Steffimycin B is an anthracycline metabolite isolated from a Streptomyces sp. with antibacterial and antineoplastic properties. Crystallographic studies of binding to DNA suggest that it has a higher CpG base sequence specificity over the TpA step
JIB-04