SENP8 Protein | Proton-pump inhibitor proton-pump.com

Name :
SENP8 Protein

Description :
Sentrin-Specific Protease 8 (SENP8) mediates the reversible covalent modification of proteins by NEDD8. SENP8 catalyzes the full-length NEDD8 to generate its mature form and deconjugation of NEDD8 from targeted proteins such as CUL2 , CUL4A in vivo, or p53. but it does not show activity against ubiquitin or SUMO proteins.

Species :
Human

Uniprotkb :
E. coli

Tag :
N-6His

Synonyms :
DEN1, Protease Cysteine 2, NEDP1, Sentrin-Specific Protease 8, Deneddylase-1, PRSC2, SENP8, NEDD8-Specific Protease 1, Sentrin/SUMO-Specific Protease SENP8

Construction :
Recombinant Human Sentrin-Specific Protease 8 is produced by our E.coli expression system and the target gene encoding Met1-Lys212 is expressed with a 6His tag at the N-terminus.

Protein Purity :
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)

Molecular Weight :
22 KDa, reducing conditions

Endotoxin :
Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.

Formulatione :
Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Reconstitution :

Stability & Storage :
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Shipping :
The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below.

Research Background :
Sentrin-Specific Protease 8 (SENP8) mediates the reversible covalent modification of proteins by NEDD8. SENP8 catalyzes the full-length NEDD8 to generate its mature form and deconjugation of NEDD8 from targeted proteins such as CUL2 , CUL4A in vivo, or p53. but it does not show activity against ubiquitin or SUMO proteins.

References and Literature :

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