PLXNA1 Protein | Proton-pump inhibitor proton-pump.com

Name :
PLXNA1 Protein

Description :
PlexinA1 (PlxnA1) is a transmembrane receptor for semaphorins, a large family of proteins that act as axonal guidance cues during nervous system development.

Species :
Mouse

Uniprotkb :
HEK293

Tag :
C-His

Synonyms :
Kiaa4053, Plexin-A1, PlexinA1, NOVP, Plex 1, NOV, Plexin-1

Construction :
Recombinant Mouse PLXNA1 Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Ser28-Pro1242.[Accession |P70206]

Protein Purity :
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC

Molecular Weight :
The protein has a predicted MW of 134.90 kDa. Due to glycosylation, the protein migrates to 140-160 kDa based on Tris-Bis PAGE result.

Endotoxin :
Less than 1EU per μg by the LAL method.

Formulatione :
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

Reconstitution :
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.

Stability & Storage :
-20 to -80°C for 12 months as supplied from date of receipt. -20 to -80°C for 3-6 months in unopened state after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Shipping :
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Research Background :
PlexinA1 (PlxnA1) is a transmembrane receptor for semaphorins, a large family of proteins that act as axonal guidance cues during nervous system development.

References and Literature :
1. Jahan MS, et al. PlexinA1 deficiency in BALB/cAJ mice leads to excessive self-grooming and reduced prepulse inhibition. IBRO Rep. 2020 Oct 22;9:276-289. doi: 10.1016/j.ibror.2020.10.004. PMID: 33163687; PMCID: PMC7607060.

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