Name :
ACE2 (K353G) (Human) Recombinant Protein

Biological Activity :
Human ACE2 (Q9BYF1-1, 18 a.a. – 740 a.a.) K353G mutant partial recombinant protein with C-terminus hFc tag expressed in 293F cells.Recombinant Human Protein,Recombinant Human Proteins,Human Recombinant Protein,Human Recombinant Proteins,HuPro

Tag :
The protein has a calculated MW of 111.7 kDa. The protein migrates as 125-150 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Protein Accession No. :
Q9BYF1-1

Protein Accession No.URL :
https://www.ncbi.nlm.nih.gov/gene?cmd=Retrieve&dopt=Graphics&list_uids=59272

Amino Acid Sequence :

Molecular Weight :
111.7, 125-150 (R)

Storage and Stability :
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Host :
Human

Interspecies Antigen Sequence :

Preparation Method :
Mammalian cell (293F) expression system

Purification :
Ni-NTA affinity purification

Quality Control Testing :
2 ug loaded SDS-PAGE

Storage Buffer :
In PBS, pH 7.4.

Applications :
Western Blot (Recombinant protein)， Western Blot analysis of Lane 1: 293F negative control, Lane 2: 293F transfection IgG2-ACE2-353G-hFC supernatant of cell cracking fluid and Lane 3: 293F transfection IgG2-ACE2-353G-hFC cell supernatant.Primary antibody: ACE2 polyclonal antibody (Cat # PAB31772) (1:1000)Second antibody: Goat anti-Rabbit IgG (H+L)-HPR(1:20000)Exposure time: 3 s Enzyme-linked Immunoabsorbent Assay， SDS-PAGE，

Gene Name :
ACE2

Gene Alias :
ACEH, DKFZp434A014

Gene Description :
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2

Gene Summary :
The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. [provided by RefSeq

Other Designations :
ACE-related carboxypeptidase|OTTHUMP00000022963|angiotensin I converting enzyme 2|angiotensin converting enzyme-like protein

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
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