Additional Information:
accession O75578(ITGA10)&P05556(ITGB1)|express systemHEK293|product tagC-His|purity> 90% as determined by Tris-Bis PAGE|backgroundAlpha 10 beta 1 is currently known as four collagen-binding I domain-containing integrins, the others are namely alpha 1 beta 1, alpha 2 beta 1 and alpha 11 beta 1. 101 is likely to be expressed only by a subset of fibroblasts.|molecular weightThe protein has a predicted MW of 125.60 kDa (ITGA10) & 83.2 kDa (ITGB1). Due to glycosylation, the protein migrates to 140-160 kDa (ITGA10) and 100-130 kDa (ITGB1) based on Tris-Bis PAGE result.|available size100 g, 500 g|endotoxinLess than 1EU per g by the LAL method.|Human Integrin alpha 10 beta 1 (ITGA10&ITGB1) Heterodimer Protein 5076proteinSize and concentration100, 500g and lyophilizedFormLyophilizedStorage InstructionsValid for 12 months from date of receipt when stored at -80C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.Storage bufferShipped at ambient temperature.Purity> 95% as determined by Tris-Bis PAGEtarget relevanceAlpha 10 beta 1 is currently known as four collagen-binding I domain-containing integrins, the others are namely alpha 1 beta 1, alpha 2 beta 1 and alpha 11 beta 1. 101 is likely to be expressed only by a subset offibroblasts.Protein namesIntegrin alpha-10Gene namesITGA10,ITGA10 UNQ468/PRO827Protein familyIntegrin alpha chain familyMass127602DaFunctionIntegrin alpha-10/beta-1 is a receptor for collagen.Subellular locationMembrane; Single-pass type I membrane protein.TissuesWidely expressed with highest expression in muscle and heart. Found in articular cartilage.StructureHeterodimer of an alpha and a beta subunit. Alpha-10 associates with beta-1.DomainThe integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo proTarget Relevance information above includes information from UniProt accession: O75578The UniProt Consortium|