Product Name :
Betulinic acid
Synonym:
3β-Hydroxy-20(29)-lupaene-28-oic acid
CAS :
472-15-1
Molecular formula:
C30H48O3
Molecular Weight :
456.{{1500080-17-0} MedChemExpress|{1500080-17-0} Biological Activity|{1500080-17-0} In Vivo|{1500080-17-0} custom synthesis} 71
Purity:
≥98% (HPLC)
Specifications:
Purity ≥98% (HPLC)|Appearance White powder|Identity 1H-NMR|PropertiesSolvents DMSO (20 mg/ml), DMF (15 mg/ml)|
Product Name :
7-Benzyloxy-4-trifluoromethycoumarin
Synonym:
BFC
CAS :
220001-53-6
Molecular formula:
C17H11F3O3
Molecular Weight :
320.{{38396-39-3} site|{38396-39-3} Purity & Documentation|{38396-39-3} In Vivo|{38396-39-3} supplier} 26
Purity:
≥97% (NMR)
Specifications:
Purity ≥97% (NMR)|Appearance White to off-white powder|Identity 1H-NMR|PropertiesSolvents Soluble in DMSO.{{2070852-76-3} MedChemExpress|{2070852-76-3} Protocol|{2070852-76-3} References|{2070852-76-3} supplier} |DownloadsSafety Data Sheet CDX B0299 MSDS.PMID:30860746 pdf|
Product Name :
4,5-Dimethyl-2-nitroaniline
Synonym:
6-Nitro-3,4-xylidine
CAS :
6972-71-0
Molecular formula:
C8H10N2O2
Molecular Weight :
166.18
Purity:
≥98%
Specifications:
Purity ≥98%|Appearance Orange to brown powder|Identity 1H-NMR|PropertiesSolvents DMSO|Melting Point 139-141 °C (lit.{{2745060-92-6} web|{2745060-92-6} Biological Activity|{2745060-92-6} In stock|{2745060-92-6} supplier} )|
Product Name :
Dimethyl Citric acid
Description:
Dimethylurea/citric acid is a highly efficient deep eutectic solvent (DES). Dimethylurea/citric acid can be used as a catalyst and a green reaction medium for the synthesis of bis(indolyl)methanes, quinolines and aryl-4, 5-diphenyl-1H-imidazoles.
CAS:
53798-97-3
Molecular Weight:
220.18
Formula:
C8H12O7
Chemical Name:
3-hydroxy-5-methoxy-3-(methoxycarbonyl)-5-oxopentanoic acid
Smiles :
COC(=O)CC(O)(CC(O)=O)C(=O)OC
InChiKey:
OMIHCBSQSYMFDP-UHFFFAOYSA-N
InChi :
InChI=1S/C8H12O7/c1-14-6(11)4-8(13,3-5(9)10)7(12)15-2/h13H,3-4H2,1-2H3,(H,9,10)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Toceranib} medchemexpress|{Toceranib} PDGFR|{Toceranib} Technical Information|{Toceranib} Formula|{Toceranib} custom synthesis|{Toceranib} Cancer}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Dimethylurea/citric acid is a highly efficient deep eutectic solvent (DES).{{Hydroxyurea} site|{Hydroxyurea} Cell Cycle/DNA Damage|{Hydroxyurea} Purity & Documentation|{Hydroxyurea} In stock|{Hydroxyurea} custom synthesis|{Hydroxyurea} Cancer} Dimethylurea/citric acid can be used as a catalyst and a green reaction medium for the synthesis of bis(indolyl)methanes, quinolines and aryl-4, 5-diphenyl-1H-imidazoles.PMID:32658556 |Product information|CAS Number: 53798-97-3|Molecular Weight: 220.18|Formula: C8H12O7|Chemical Name: 3-hydroxy-5-methoxy-3-(methoxycarbonyl)-5-oxopentanoic acid|Smiles: COC(=O)CC(O)(CC(O)=O)C(=O)OC|InChiKey: OMIHCBSQSYMFDP-UHFFFAOYSA-N|InChi: InChI=1S/C8H12O7/c1-14-6(11)4-8(13,3-5(9)10)7(12)15-2/h13H,3-4H2,1-2H3,(H,9,10)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
Product Name :
PF-02413873
Description:
PF-02413873 (PF-2413873) is a potent selective, fully competitive and orally active nonsteroidal progesterone receptor (PR) antagonist, with a Ki of 2.6 nM. PF-02413873 can block progesterone binding and PR nuclear translocation, and inhibit endometrial growth in vivo.
CAS:
936345-35-6
Molecular Weight:
359.44
Formula:
C18H21N3O3S
Chemical Name:
4-{[3-cyclopropyl-1-(methanesulfonylmethyl)-5-methyl-1H-pyrazol-4-yl]oxy}-2,6-dimethylbenzonitrile
Smiles :
CC1C=C(C=C(C)C=1C#N)OC1C(=NN(CS(C)(=O)=O)C=1C)C1CC1
InChiKey:
QSFGZNVRVZHUGV-UHFFFAOYSA-N
InChi :
InChI=1S/C18H21N3O3S/c1-11-7-15(8-12(2)16(11)9-19)24-18-13(3)21(10-25(4,22)23)20-17(18)14-5-6-14/h7-8,14H,5-6,10H2,1-4H3
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Tropisetron} MedChemExpress|{Tropisetron} 5-HT Receptor|{Tropisetron} Purity & Documentation|{Tropisetron} Description|{Tropisetron} supplier|{Tropisetron} Cancer}
Shelf Life:
≥12 months if stored properly.{{(-)-Epigallocatechin} medchemexpress|{(-)-Epigallocatechin} Autophagy|{(-)-Epigallocatechin} Technical Information|{(-)-Epigallocatechin} Description|{(-)-Epigallocatechin} supplier|{(-)-Epigallocatechin} Epigenetic Reader Domain}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
PF-02413873 (PF-2413873) is a potent selective, fully competitive and orally active nonsteroidal progesterone receptor (PR) antagonist, with a Ki of 2.6 nM. PF-02413873 can block progesterone binding and PR nuclear translocation, and inhibit endometrial growth in vivo.|Product information|CAS Number: 936345-35-6|Molecular Weight: 359.44|Formula: C18H21N3O3S|Chemical Name: 4-{[3-cyclopropyl-1-(methanesulfonylmethyl)-5-methyl-1H-pyrazol-4-yl]oxy}-2,6-dimethylbenzonitrile|Smiles: CC1C=C(C=C(C)C=1C#N)OC1C(=NN(CS(C)(=O)=O)C=1C)C1CC1|InChiKey: QSFGZNVRVZHUGV-UHFFFAOYSA-N|InChi: InChI=1S/C18H21N3O3S/c1-11-7-15(8-12(2)16(11)9-19)24-18-13(3)21(10-25(4,22)23)20-17(18)14-5-6-14/h7-8,14H,5-6,10H2,1-4H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 100 mg/mL (278.PMID:32701010 21 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PF-02413873 shows potent PR antagonist activity with a derived Ki of 9.7 nM in the T47D native functional assay. PF-02413873 (1 nM-10 μM) induces nuclear translocation only at high concentrations (>3 μM).|In Vivo:|PF-02413873 (2.5 and 10 mg/kg; p.o. twice daily for 10 days) induces a statistically significant reduction in endometrial thickness in cynomolgus macaques. PF-02413873 (3 mg/kg; a single p.o.) exhibits t1/2 (4.2 h), Cmax (162 ng/mL) and CL/F (41 mL/min/kg).|Products are for research use only. Not for human use.|
Product Name :
Anti-ANGPTL3, Human antibody
Applications:
ELISA,Flow Cyt
Reactivity :
Human
Conjugate:
Unconjugated
Advantages :
High lot-to-lot consistencyIncreased sensitivity and higher affinityAnimal-free production
Description:
| Description: Anti-ANGPTL3, Human antibody is designed for detecting human ANGPTL3 specifically. Based on ELISA and/or FCM, Anti-ANGPTL3, Human antibody reacts with human ANGPTL3 specifically. | Immunogen: Recombinant human ANGPTL3 | Host: Alpaca pacous | Isotype: Human IgG1 | Conjugate: Unconjugated | Specificity: Human ANGPTL3 | Purity: Recombinant Expression and Affinity purified | Concentration: 1mg/ml | Formation: Liquid, 10mM PBS (pH 7.5), 0.05% sucrose, 0.1% trehalose, 0.01% proclin300, 50% Glycerol | Storage: Store at –20 °C, (Avoid freeze / thaw cycles) | Background:ANGPTL3 encodes a member of a family of secreted proteins that function in angiogenesis. The encoded protein, which is expressed predominantly in the liver, is further processed into an N-terminal coiled-coil domain-containing chain and a C-terminal fibrinogen chain. The N-terminal chain is important for lipid metabolism, while the C-terminal chain may be involved in angiogenesis. Mutations in this gene cause familial hypobetalipoproteinemia type 2.{{1019206-88-2} MedChemExpress|{1019206-88-2} Protocol|{1019206-88-2} Formula|{1019206-88-2} supplier}
Description2 :
Anti-ANGPTL3, Human antibody is designed for detecting human ANGPTL3 specifically.{{1627091-47-7} MedChemExpress|{1627091-47-7} Biological Activity|{1627091-47-7} In Vitro|{1627091-47-7} custom synthesis} Based on ELISA and/or FCM, Anti-ANGPTL3, Human antibody reacts with human ANGPTL3 specifically.PMID:29999848
Immunogen:
Recombinant human ANGPTL3
Host :
Alpaca pacous
Isotype:
Human IgG1
Purity :
Recombinant Expression and Affinity purified
Buffer :
Storage :
Store at –20 °C, (Avoid freeze / thaw cycles)
Function:
ELISA: 1:4,000-1:10000Flow Cytometry：1:200-1:1000Dilution factors are presented in the form of a range because the optimal dilution is a function of many factors, such as antigen density, permeability, etc. The actual dilution used must be determined empirically.
Product Name :
Cyclooctyne-O-PFP ester
Description:
Cyclooctyne-O-PFP ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
CAS:
886209-60-5
Molecular Weight:
348.26
Formula:
C16H13F5O3
Chemical Name:
2,3,4,5,6-pentafluorophenyl 2-(cyclooct-2-yn-1-yloxy)acetate
Smiles :
O=C(COC1CCCCCC#C1)OC1C(F)=C(F)C(F)=C(F)C=1F
InChiKey:
FTKRNGMQMZGSDF-UHFFFAOYSA-N
InChi :
InChI=1S/C16H13F5O3/c17-11-12(18)14(20)16(15(21)13(11)19)24-10(22)8-23-9-6-4-2-1-3-5-7-9/h9H,1-4,6,8H2
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Congo Red} medchemexpress|{Congo Red} {Fluorescent Dye}|{Congo Red} Protocol|{Congo Red} In stock|{Congo Red} supplier|{Congo Red} Cancer}
Shelf Life:
≥12 months if stored properly.{{Atosiban} web|{Atosiban} Vasopressin Receptor|{Atosiban} TGF-beta/Smad|{Atosiban} Purity & Documentation|{Atosiban} Purity|{Atosiban} custom synthesis}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:33203292
Additional information:
Cyclooctyne-O-PFP ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).|Product information|CAS Number: 886209-60-5|Molecular Weight: 348.26|Formula: C16H13F5O3|Chemical Name: 2,3,4,5,6-pentafluorophenyl 2-(cyclooct-2-yn-1-yloxy)acetate|Smiles: O=C(COC1CCCCCC#C1)OC1C(F)=C(F)C(F)=C(F)C=1F|InChiKey: FTKRNGMQMZGSDF-UHFFFAOYSA-N|InChi: InChI=1S/C16H13F5O3/c17-11-12(18)14(20)16(15(21)13(11)19)24-10(22)8-23-9-6-4-2-1-3-5-7-9/h9H,1-4,6,8H2|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 100 mg/mL (287.14 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.|Products are for research use only. Not for human use.|
Product Name :
Agaric acid
Description:
Agaric acid (Agaricinic Acid) is obtained from various plants of the fungous tribe, i.e. Polyporus officinalis and Polyporus igniarius. Agaric acid induces mitochondrial permeability transition through its interaction with the adenine nucleotide translocase. Agaric acid promotes efflux of accumulated Ca2+, collapse of transmembrane potential, and mitochondrial swelling. Agaric acid is used to regulate lipid metabolism.
CAS:
666-99-9
Molecular Weight:
416.55
Formula:
C22H40O7
Chemical Name:
1-hexadecyl-2-hydroxypropane-1,2,3-tricarboxylic acid
Smiles :
CCCCCCCCCCCCCCCCC(C(O)=O)C(O)(CC(O)=O)C(O)=O
InChiKey:
HZLCGUXUOFWCCN-UHFFFAOYSA-N
InChi :
InChI=1S/C22H40O7/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-18(20(25)26)22(29,21(27)28)17-19(23)24/h18,29H,2-17H2,1H3,(H,23,24)(H,25,26)(H,27,28)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Agaric acid (Agaricinic Acid) is obtained from various plants of the fungous tribe, i.e. Polyporus officinalis and Polyporus igniarius. Agaric acid induces mitochondrial permeability transition through its interaction with the adenine nucleotide translocase. Agaric acid promotes efflux of accumulated Ca2+, collapse of transmembrane potential, and mitochondrial swelling. Agaric acid is used to regulate lipid metabolism.|Product information|CAS Number: 666-99-9|Molecular Weight: 416.55|Formula: C22H40O7|Chemical Name: 1-hexadecyl-2-hydroxypropane-1,2,3-tricarboxylic acid|Smiles: CCCCCCCCCCCCCCCCC(C(O)=O)C(O)(CC(O)=O)C(O)=O|InChiKey: HZLCGUXUOFWCCN-UHFFFAOYSA-N|InChi: InChI=1S/C22H40O7/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-18(20(25)26)22(29,21(27)28)17-19(23)24/h18,29H,2-17H2,1H3,(H,23,24)(H,25,26)(H,27,28)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Tenofovir Disoproxil} site|{Tenofovir Disoproxil} HIV|{Tenofovir Disoproxil} Protocol|{Tenofovir Disoproxil} References|{Tenofovir Disoproxil} manufacturer|{Tenofovir Disoproxil} Epigenetics} |Shelf Life: ≥12 months if stored properly.{{Penfluridol} MedChemExpress|{Penfluridol} Autophagy|{Penfluridol} Activator|{Penfluridol} Technical Information|{Penfluridol} Description|{Penfluridol} manufacturer} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:32565113 |Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
Product Name :
JSH-23
CAS No.:
749886-87-1
Purity :
> 97%
Shipping:
Shipped on dry ice.
Storage :
Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month
SMILES:
CC1=CC=C(NCCCC2=CC=CC=C2)C(=C1)N
Product Description :
JSH-23 is an inhibitor of NF-κB transcriptional activity with IC50 of 7.1 μM in RAW 264.7 cell line.
Formula:
C16H20N2
Molecular Weight :
240.34
Synonyms:
Additional Information:
|CAS No. 749886-87-1 ; |Formula C16H20N2 ; |Molecular Weight 240.{{4547-24-4} medchemexpress|{4547-24-4} Technical Information|{4547-24-4} References|{4547-24-4} custom synthesis} 34 ; |SMILES CC1=CC=C(NCCCC2=CC=CC=C2)C(=C1)N ; |Target NFkB ; |Product Description JSH-23 is an inhibitor of NF-κB transcriptional activity with IC50 of 7.{{112-80-1} medchemexpress|{112-80-1} Purity & Documentation|{112-80-1} Formula|{112-80-1} custom synthesis} 1 μM in RAW 264.PMID:30499762 7 cell line. ; |Purity > 97% ; |Shipping Shipped on dry ice. ; |Storage Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month ; |Solubility Overview Soluble in DMSO
Product Name :
Anti-Mouse IgG kappa, AlpSdAbs® VHH(iFluor647)
Applications:
WB,ICC/IF,ELISA,Flow Cyt
Reactivity :
Mouse kappa
Conjugate:
iFluor647
Advantages :
High lot-to-lot consistencyIncreased sensitivity and higher affinityAnimal-free production
Description:
| Description: Anti-Mouse IgG kappa, AlpSdAbs® VHH(iFluor647) is designed for detecting mouse IgG kappa chain specifically, and Anti-Mouse IgG kappa, AlpSdAbs® VHH(iFluor647) is useful for super-resolution microscopy. Anti-Mouse IgG kappa, AlpSdAbs® VHH(iFluor647) is based on recombinant single domain antibody to mouse IgG kappa chain coupled to iFluor647. Based on immunoelectrophoresis and/or ELISA, Anti-Mouse IgG kappa, AlpSdAbs® VHH(iFluor647) reacts with the mouse IgG kappa chain selectively, no reactivity with the mouse IgG lambda chain or heavy chain of mouse IgG. | Immunogen: Fab region of Mouse IgG | Host: Alpaca pacous | Isotype: VHH domain of alpaca IgG2b/2c | Conjugate: iFluor647(Ex:651nm, Em:667nm) | Specificity: Mouse IgG kappa chain | Cross-Reactivity: No cross-reactivity with rabbit, human, cynomolgus, rat, goat IgG | Purity: Recombinant Expression and Affinity purified | Concentration: 0.5mg/mL | Formation: Liquid, 10mM PBS (pH 7.5), 0.05% sucrose, 0.1% trehalose, 0.01% proclin300, 50% glycerol | Storage: Store at –20 °C(Avoid freeze / thaw cycles) , Protect from light. | Background:VHH are single-domain antibodies derived from the variable regions of heavy chain of Camelidae immunoglobulin. The size of VHH is extremely small(The smaller size of the VHH decreases linkage error and increases staining accuracy effectively. Standard immunodetection approaches use typically a primary antibody (1.Ab) which binds the protein of interest (POI) and a secondary antibody (2.Ab) that binds to the 1.Ab and carries a detection element. The complex formed by the primary antibody and the secondary antibody (1.Ab–2.Ab) is widely used because it is a cost effective and flexible approach since only the 2.Abs need to be coupled to the detection element. However, the use of this complex carries some relevant limitations. The 1.Ab–2.Ab can measure up to 30 nm, leading to a large distance between the targeted molecule and the detection element, causing the so called “linkage” or “displacement” error. While this might not influence the results in some applications (e.g. epifluorescence, ELISA or FACS), it is of major relevance for super-resolution microscopy techniques where the localization precision can be as high as 1 nm. The linkage error can be reduced by using directly labelled small affinity probes like camelid single domain antibodies (sdAbs) also known as nanobodies (Nbs), which have sizes below 3 nm.
Description2 :
Anti-Mouse IgG kappa, AlpSdAbs® VHH(iFluor647) is designed for detecting mouse IgG kappa chain specifically, and Anti-Mouse IgG kappa, AlpSdAbs® VHH(iFluor647) is useful for super-resolution microscopy.{{519-62-0} web|{519-62-0} Purity & Documentation|{519-62-0} In Vitro|{519-62-0} supplier} Anti-Mouse IgG kappa, AlpSdAbs® VHH(iFluor647) is based on recombinant single domain antibody to mouse IgG kappa chain coupled to iFluor647. Based on immunoelectrophoresis and/or ELISA, Anti-Mouse IgG kappa, AlpSdAbs® VHH(iFluor647) reacts with the mouse IgG kappa chain selectively, no reactivity with the mouse IgG lambda chain or heavy chain of mouse IgG.{{1073154-85-4} MedChemExpress|{1073154-85-4} Protocol|{1073154-85-4} In stock|{1073154-85-4} custom synthesis}
Immunogen:
Fab region of Mouse IgG
Host :
Alpaca pacous
Isotype:
VHH domain of alpaca IgG2b/2c
Purity :
Recombinant Expression and Affinity purified
Buffer :
Storage :
Store at –20 °C(Avoid freeze / thaw cycles) , Protect from light.PMID:29262051
Function:
Flow Cyt: 1:200-1:2000ICC/IF： 1:200-1:2000ELISA： 1:5000-1:20000WB: 1:5000-1:20000 | Super-resolution microscopyDilution factors are presented in the form of a range because the optimal dilution is a function of many factors, such as antigen density, permeability, etc. The actual dilution used must be determined empirically.